Aeroplysinin-1, a Sponge-Derived Multi-Targeted Bioactive Marine Drug
نویسندگان
چکیده
منابع مشابه
Aeroplysinin-1, a Sponge-Derived Multi-Targeted Bioactive Marine Drug.
Organisms lacking external defense mechanisms have developed chemical defense strategies, particularly through the production of secondary metabolites with antibiotic or repellent effects. Secondary metabolites from marine organisms have proven to be an exceptionally rich source of small molecules with pharmacological activities potentially beneficial to human health. (+)-Aeroplysinin-1 is a se...
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(+)-aeroplysinin-1, an antibacterial brominated compound produced by certain sponges, was selected during a blind high-throughput screening for new potential antiangiogenic compounds obtained from marine organisms. In a variety of experimental systems, representing the sequential events of the angiogenic process, aeroplysinin-1 treatment of endothelial cells resulted in strong inhibitory effect...
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ژورنال
عنوان ژورنال: Marine Drugs
سال: 2015
ISSN: 1660-3397
DOI: 10.3390/md14010001